University of South Florida

 
Division of Comparative Medicine
“…contributing to a greater reverence for life.”



Standard Operating Procedures

The program and facilities of Comparative Medicine are guided by the following Standard Operating Procedures.

Management & Administrative

• SOP 001 Document Controls
• SOP 002 Quality Assurance Unit for GLP Nonclinical Laboratory Studies
• SOP 003 Facilities for Aseptic Surgery
• SOP 004 Pest Control
• SOP 005 Animal Quarantine, Stabilization and Separation
• SOP 006 Animal Health and Environmental Surveillance
• SOP 007 Transportation, Relocation, or Reassignment of Animals
• SOP 008 Test & Control Articles
• SOP 009 Clinical Laboratory Sample Testing
• SOP 010 Handling, Storage, and Retrieval of Records and Data
• SOP 011 Reagent Labeling
• SOP 012 Animal Medical Records for Nonrodent Mammals
• SOP 013 Employee Orientation and Training
• SOP 014 Controlled Substances
• SOP 015 Animal Identification
• SOP 016 Animal Room Preparation
• SOP 017 Handling of Animals Found Moribund or Dead
• SOP 018 Necropsy and Post Mortem Examination
• SOP 019 Histopathology
• SOP 020 Training of GLP Testing Facility Personnel
• SOP 021 Collection and Identification of Specimens
• SOP 022 Feed and Bedding
• SOP 023 Production of Polyclonal Antibodies in Rabbits
• SOP 024 Use of Expired Medical and Research Supplies
• SOP 025 Photography of Animals or Within Animal Facilities
• SOP 026 Laboratory Animal Adoption Program
• SOP 027 Guidelines for Performing Survival Surgery in Non-Rodent and USDA Regulated Species
• SOP 028 Thermal Regulation of the Anesthetized Patient
• SOP 029 Reporting/Tracking Work Related Injury/Illness
• SOP 030 Inspection of Animal Facilities by Outside Agencies
• SOP 031 Response to Suspect Exposure to Uncharacterized Human Blood, Tissue and Body Fluids  

Rabbits

• SOP 100 Rabbit Husbandry

Cats

• SOP 200 Cat Husbandry

Ferrets

• SOP 250 Ferret Husbandry

Dogs

• SOP 300 Dog Husbandry

Rodents

• SOP 400 Rodent Husbandry
• SOP 401 Carbon Dioxide (CO2) Euthanasia in Rodent Species
• SOP 402 Sentinel Rodent Exposure
• SOP 403 Rodent Enrichment
• SOP 404 USDA Rodent Species Medical Records
• SOP 408 Biosafety Level-2 (BSL-2) Rodent Husbandry
• SOP 410 Sentinel Rodent Health Surveillance
• SOP 411 Rodent Quarantine
• SOP 412 Rodent Surgery
• SOP 413 Sterilized Micro-Isolator Rodent Cage Changing
• SOP 415 Hazardous Test Substance Rodent Husbandry
• SOP 417 Preparing Acidified Drinking Water for Rodents
• SOP 418 Mouse Tissue Collection for Genetic Analysis  
• SOP 419 Biosafety Level-1 (BSL-1) Rodent Husbandry at the IDRB   
• SOP 420 Biosafety Level-2 (BSL-2) Rodent Husbandry at the IDRB 
• SOP 421 Biosafety Level 3 Animal Husbandry at IDRB  
• SOP 450 Guinea Pig Husbandry

Birds

• SOP 500 Avian Husbandry  
• SOP 501 House Sparrow Husbandry    

Nonhuman Primates

• SOP 600 Nonhuman Primate Room Duties
• SOP 601 Quarantine and Testing of Nonhuman Primates
• SOP 602 Nonhuman Primate Physicals
• SOP 603 Protective Clothing When Working with Nonhuman Primates
• SOP 604 Nonhuman Primate Feeding and Watering Procedures
• SOP 605 Nonhuman Primate Cage Cleaning
• SOP 606 Nonhuman Primate Health and Behavioral Surveillance
• SOP 609 Response Following Suspect Exposure to Cercopithecine Herpesvirus-1
• SOP 610 TB Testing for Nonhuman Primates
• SOP 613 Environmental Enrichment for Nonhuman Primates
• SOP 614 Nonhuman Primate Exposure Response Kit Maintenance
• SOP 615 Nonhuman Primate Transportation
• SOP 616 Handling, Storage, and Shipping Samples for B Virus Testing
• SOP 617 Compatibility Testing of Nonhuman Primates
• SOP 618 Nonhuman Primate Manual Cage Wash and Sanitation

Livestock

• SOP 700 Livestock Husbandry
• SOP 708 Care and Use of Pregnant Sheep

Aquatic Species

• SOP 800 Aquatic Vertebrate Room Duties
• SOP 801 Xenopus Frog Care and Feeding
• SOP 802 Leopard Frog Care and Feeding
• SOP 803 Zebrafish Care and Feeding
• SOP 804 Aquatic Habitats™ System  
• SOP 805 Techniplast Xenoplus™ Stand Alone Housing System

Occupational Health & Safety

• SOP 901 Utilization of Material Safety Data Sheets (MSDS)
• SOP 902 Procedures for Handling Syringes, Needles, and Sharps
• SOP 903 Basic Guidelines to Follow While Working Within Animal Rooms
• SOP 904 Standard Safety Practices in Animal Rooms
• SOP 905 Health, Hygiene and Laboratory Attire
• SOP 906 Hazard Communication (HAZCOM)
• SOP 907 Fire Evacuation Plan  
• SOP 908 Decontamination of BSL-3Caging Equipment 
  
• SOP 909 Anesthetic Gas Monitoring and Safety 

Operations & Equipment

• SOP 1001 Use of Acid Scale Remover
• SOP 1002 Monitoring Autoclave Sterilization
• SOP 1003 Cagewash Detergents
• SOP 1004 Monitoring Cagewash Efficacy
• SOP 1005 Cagewash Operation
• SOP 1006 Autoclave Sterilization
• SOP 1007 Verify® Steam Test Pack Biological Indicators
• SOP 1008 Use of Personal Protective Equipment
• SOP 1009 Decontamination
• SOP 1010 Microbiological Monitoring of Sanitation Procedures
• SOP 1011 RODAC Plate Procedures
• SOP 1012 Manual Cage Washing & Sanitation
• SOP 1013 Monitoring Steam Sterilization of Liquids
• SOP 1014 Monitoring Animal Drinking Water Quality  
• SOP 1015 Decontamination of Common Procedural Areas  
• SOP 1101 Veterinary Anesthetic Scavenging Unit
• SOP 1102 Veterinary Anesthesia Machine & Technique
• SOP 1103 Equipment_Maintenance_Calibration
• SOP 1104 Veterinary Electronic Thermometer
• SOP 1105 Veterinary Capnograph
• SOP 1106 Ultrasonic Doppler Flow Detector
• SOP 1107 Veterinary Dental Scaler and Polisher
• SOP 1108 Veterinary ECG/SpO2 Monitor/Recorder
• SOP 1109 Veterinary Blood Pressure Monitor
• SOP 1110 Veterinary Anesthetic Ventilator
• SOP 1111 C-Arm Fluoroscope
• SOP 1112 Veterinary Electro-Cautery Unit
• SOP 1113 Paramount™ Filtered Enclosure
• SOP 1114 Refrigerator and Freezer Unit Use and Monitoring
• SOP 1115 Thermometer/Hygrometer Calibration
• SOP 1116 Traceable® Big-Digit Hygrometer/Thermometer
• SOP 1117 Traceable® Refrigerator/Freezer Thermometer
• SOP 1118 Amsco® Eagle Autoclave Model #2021
• SOP 1119 Cyclone™ Aerosol Fogger
• SOP 1120 Amsco® Stage III Autoclave Model #SV3033
• SOP 1121 Amsco® Autoclave Model #3041
• SOP 1122 Vehicle Care and Maintenance
• SOP 1124 GAYMAR® Circulating Thermal Water Pads
• SOP 1125 Astec Microflow® Monaire Fume Hood
• SOP 1126 NuAire® Horizontal Laminar Flow Clean Work Bench
• SOP 1127 Biological Safety Cabinets
• SOP 1129 NuAire® Small Animal Cage Changing Station
• SOP 1130 AIMS® Veterinary Tattoo Machine
• SOP 1131 Vet Temp® Infrared Ear Thermometer
• SOP 1133 Amsco® Autoclave Model #2322
• SOP 1134 Amsco® Eagle SG-120 Autoclave Model #2021
• SOP 1135 Portable IMPAC 6® Veterinary Anesthesia Machine
• SOP 1136 Branson® Ultrasonic Instrument Cleaner
• SOP 1137 Xenogen® Bioluminescence Imaging System Procedures
• SOP 1138 Xenogen® Bioluminescence Imaging Gas Anesthesia System
• SOP 1139 Charm Sciences Lum-T Luminometer
• SOP 1140 Surgivet Multi-Station Lab Research Anesthesia System & Techniques for Rodents
• SOP 1141 Amsco® Eagle Stage III Autoclave Model SV3053
• SOP 1142 Kirschner/Scientific Recovery Unit
• SOP 1143 Ohio IC Pediatric Incubator
• SOP 1144 SurgiVet V3395 Pulse Oximeter Patient Monitor (Blue)
• SOP 1145 HOBO Data Logger Model U9-002 (Light On/Off Sensor)
• SOP 1146 PRL Power Foamer  
• SOP 1147 Amsco® Century Model SV-148 Pre-Vac Steam Sterilizer 
• SOP 1148 Consolidated Sterilizer® Autoclave Model SR-24CMCV  
• SOP 1149 Amsco® Eagle SV 120 Scientific Prevacuun Sterilizer
• SOP 1150 Amsco® Model #85 Inch Century Bulk Sterilizer  

Leave Request Form   

Please address questions to CompMed@research.usf.edu, telephone (813) 974-9796, fax (813) 974-9432; IACUC@research.usf.edu, telephone (813) 974-7106, fax (813) 974-7091.