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Division of Comparative Medicine

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Applications to the Institutional Animal Care & Use Committee

Format: Use the following editable documents to apply to the IACUC. Application forms are provided in Adobe Acrobat®   and Microsoft Word®   formats.   

Note: The IACUC application is a readily accessible document that describes and justifies the purpose(s) and procedure(s) for which animals are requested. It must be easily understood by non-scientists.

  • Application for the Use of Animals in Research       REVISED - Form Effective November 2007  
       Note - The Adobe® version of the application must be completed using a 10 point (or greater) font pitch.  
     
  • Application for the Study of Wild Animals In or From Natural Settings or
     
  • Application to Establish/Maintain a Mouse Colony       
      
     Note - The Adobe® version of the application must be completed using a 10 point (or greater) font pitch.
     
  • Application for Antisera Production or     REVISED - Form Effective October 2007
     
  • Application for Use of Animal Tissues or     NEW Form 

         
    TISSUE-USE-ONLY WEB PAGE 

  • VA ACORP Animal Component of Research Proposal
    • VA ACORP Appendix 9, Rodent Breeding Appendix or       
          

Need Help? There is always a veterinarian available to assist you. If you need help completing an IACUC application, or assistance in incorporating suggested revisions to your draft IACUC application, contact either
robert.engelman@moffitt.org telephone 745-4361, ctrahan@research.usf.edu telephone 974-9260, or jvanette@research.usf.edu telephone 979-9842. The guidelines linked below provide some useful suggestions and responses that may copied and pasted into a draft application.

  • Guidelines for Completing an Application to the IACUC or   

  • "Top Ten" Protocol Review Comments    

  • EXAMPLES of Completed Applications
    Mouse Models                       
    Swine Model           

  • The use of animal tissues can be viewed at the"Tissue" web site. 

One Protocol, One Grant (Usually): A single IACUC protocol cannot be used to represent the animal use activities of multiple research grants or contracts each with budgets to purchase, maintain, and use animals. A single research grant or contract may be represented by more than one IACUC-approved protocol.

If an activity involving animals that is described in an IACUC-approved protocol is supported by multiple grants with different titles (e.g., one research grant, one postdoctoral fellowship, and departmental funds), the PI must inform the IACUC by submitting a Request to Amend an Animal Use Protocol form.

If a grant not originally declared in the IACUC application is awarded later during the 3-year approval period of the protocol (i.e., grant not funded during year one of the protocol, but awarded during year two), the PI must inform the IACUC by submitting a Request to Amend an Animal Use Protocol form.

Veterinarian Review: All vertebrate animal use must first be described in a draft IACUC application and pre-reviewed by University veterinarians by attaching an electronic-version of it to an e-mail addressed to CompMed@research.usf.edu, telephone (813) 974-9796, fax (813) 974-9432. If you need help completing an IACUC application, or assistance in incorporating suggested revisions to your draft IACUC application, contact either
robert.engelman@moffitt.org telephone 745-4361, ctrahan@research.usf.edu telephone 974-9260, or jvanette@research.usf.edu telephone 979-9842.

Submitting to the IACUC
: After completion of the pre-review process, the revised application must then be submitted to Research Integrity & Compliance at MDC 35. The revised document may also be submitted as an electronic-version attached to an e-mail addressed to IACUC@research.usf.edu, with at least the original cover page signed by the Principal Investigator mailed (or FAXed 974-7091) to MDC 35.

VA Merit Applications: Principal Investigators developing applications for VA funded Merit Review grants, must submit the animal component for their research project to the IACUC using the VA ACORP.

Mouse Colonies: Colonies of mice, and all mice created locally by methods of genetic engineering involving recombinant DNA must first be represented by an IACUC-approved Application to Establish/Maintain a Mouse Colony.

IACUC Protocols with Federal or Major Agency Funding: Approval of an IACUC protocol application other than an Application to Establish/Maintain a Mouse Colony with proposed support from a federal or major funding agency is contingent on comparable protocol and proposal titles and narratives. IACUC Protocol Applications with Federal or Major Agency Funding must be accompanied by four pages from the grant proposal.

  • Face Page of form PHS 398 (or a similar page) that shows that the grant title and name of the Principal Investigator match those of the IACUC protocol application,
  • Page 2 form PHS 398 (or a similar page) wherein the project description in abstract form summarizes the scope of work to which the purpose(s) and procedure(s) described in items 7 and 8 on page 2 of the IACUC protocol will contribute,
  • First Page of the Research Plan (or a similar page) that includes the Specific Aims of the research. Note that the IACUC protocol must represent an aspect of the broad long-term objectives of the grant proposal.
  • Section F, Item 1 of the Research Plan of format PHS 398 (or a similar page) wherein a description of the proposed use of the animals and the species of animals to be used are identified.
  • Any communication/documentation from/with the granting/funding agency indicating a change in the direction of research that would affect how animals are used.

These grant application pages may be submitted to the IACUC electronically at IACUC@research.usf.edu or mailed as paper copy c/o Research Compliance at MDC35.

Mouse Colony Protocols with Any Source of Funding: An Application to Establish/Maintain a Mouse Colony need not be accompanied by a grant proposal regardless of the proposed source of funding.

IACUC Protocols with Other Funding: IACUC protocol applications with other proposed sources of funding need not be accompanied by a grant proposal, but Comparative Medicine will not fill requests for animals or service under a specific IACUC-approved protocol until an association between fiscal support, an IACUC protocol, and an account or purchase order number is assured in writing. A Research Services Agreement and/or a letter on company letterhead indicating a commitment to fund a proposal may be used to document corporate support. A memorandum from the departmental Chairperson or other signature authority on the account may be used to document departmental support of a proposal.

IACUC Members: The primary reviewing IACUC member of an application must complete the form linked below and forward an electronic-version of it to IACUC@research.usf.edu no later than the scheduled meeting time.

  • Primary Review of an IACUC Application

Please address questions to CompMed@research.usf.edu, telephone (813) 974-9796, fax (813) 974-9432; IACUC@research.usf.edu telephone (813) 974-7106, fax (813) 974-7091.