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Federal Documents and Regulations

Agricultural Bioterrorism Protection Act of 2002, 7 CFR 331 and 9 CFR 121, Final Rule

March 18, 2005

The USDA/APHIS has published the requirements for the possession, use, and transfer of biological agents and toxins that have been determined to have the potential to pose a severe threat to public health and safety, to animal health, to plant health, or to animal or plant products. This final rule will become effective April 18, 2005.

Agricultural Bioterrorism Protection Act [full text in pdf]

APHIS/USDA Agricultural Select Agent Program

Frequently Asked Questions (December, 2002)

Interim Final Rule [full text in pdf] (December 13, 2002)


Biological Defense Safety Program, 32 CFR Part 626

This regulation prescribes Department of the Army (DA) safety policy, responsibilities, and procedures for biological defense research, development, test, and evaluation (RDTE) operations.

Biological Defense Safety Program, 32 CFR Part 626 [full text in pdfs by chapter] (July 1, 1999)

Department of the Army Pamphlet 385-69
This pamphlet prescribes the minimum safety criteria and technical requirements for the Army Biological Defense Safety Program. It will be used in conjunction with this regulation to establish and implement the Biological Defense Safety Program. [full text in pdf - 37 pages] (December 31, 1993)


National Inventory of Wild Poliovirus

December, 2002

The U.S. Department of Health and Human Services (DHHS) is conducting a national inventory of biomedical laboratories to identify possession of wild poliovirus materials. The purpose of the inventory is to alert laboratories to the anticipated successful global eradication of polio and to encourage the destruction of all unneeded wild poliovirus materials. A national registry will be established to list all laboratories that retain poliovirus materials for ongoing work.

It is important to note that wild polioviruses may be present in clinical and environmental materials collected for any purpose from areas of the world where polio was endemic. These materials could include: throat swabs, respiratory secretions, feces, and environmental soil, sewage, and water samples.

The Division of Research Compliance is coordinating the survey and collecting the required information. For more information regarding this initiative, please contact Farah Moulvi, USF Institutional Biosafety Officer, at fmoulvi@research.usf.edu or (813) 974-0954.

Letter to scientific research faculty

Wild Poliovirus Inventory Form (with definitions)

CDC Informational Brochure

Laboratory Containment of Wild Polioviruses (CDC Web Site)


Public Health Security And Bioterrorism Preparedness Response Act of 2002

June 12, 2002

This law is designed to improve the ability of the United States to prevent, prepare for, and respond to bioterrorism and other public health emergencies. Section 202(a) requires all persons in possession of any select agent to notify the Secretary of DHHS by September 10, 2002. Section 213(b) requires individuals in possession of high consequence livestock pathogens or toxins and select plant pathogens to notify the Secretary of Agriculture by October 8, 2002.

Public Health Security And Bioterrorism Preparedness Response Act of 2002 [full text in pdf]

Regulated Agents List

Frequently Asked Questions


Regulated (Select) Agents

This list specifies the viruses, bacteria, fungi, toxins, genetic elements, recombinant nucleic acids, and recombinant organisms which are listed by the Department of Health and Human Services (HHS) select agents and toxins, United States Department of Agriculture (USDA) high consequence livestock pathogens, or HHS/USDA overlap agents.

Regulated Agents List


Select Agent Regulation, 42 CFR 73.0, Final Rule

March 18, 2005

The CDC has issued the requirements that govern the possession, use, and transfer of select biological agents and toxins that pose a potential threat to public health and safety. This final rule is effective as of April 18, 2005.

Select Agent Regulation [full text in pdf]

Frequently Asked Questions (December, 2002)

Interim Final Rule [full text in pdf] (December 13, 2002)


USA Patriot Act

October 26, 2001

Places restrictions on persons who possess select agents and provides criminal penalties for possession of such agents that cannot be justified for specified peaceful purposes.

USA Patriot Act [full text in pdf]

Text Specific to Biosafety: Section 817 – Expansion Of The Biological Weapons Statute



Division of Research Integrity & Compliance
Mail: 12901 Bruce B. Downs Blvd, MDC35, Tampa, FL 33612-4799   Phone: (813) 974-5638  Fax: (813) 974-5618

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Direct questions or comments about this Web site to jarnaldi@research.usf.edu  Last updated: February 22, 2008